ChemicalBook--->CAS DataBase List--->1391054-76-4

1391054-76-4

1391054-76-4 Structure

1391054-76-4 Structure
IdentificationBack Directory
[Name]

CB 80
[CAS]

1391054-76-4
[Synonyms]

CB 80
CB 8000-13C6
Glaucol-13C6
Oratrol-13C6
Daramide-13C6
Daranide-13C6
Antidrasi-13C6
Diclofenamid-13C6
DiclofenaMide-13C6
Dichlofenamide-13C6
[13C6]-Diclofenamide
Dichlorphenamide-13C6
Dichlorophenamide-13C6
1,3-DisulfaMyl-4,5-dichlorobenzene-13C6
4,5-Dichloro-1,3-disulfaMoylbenzene-13C6
4,5-Dichloro-M-benzenedisulfonaMide-13C6
1,3-DisulfaMoyl-4,5-dichlorobenzene-13C6
Dichlorphenamide-13C6 (Diclofenamide-13C6)
3,4-Dichloro-5-sulfaMylbenzenesulfonaMide-13C6
[Molecular Formula]

C6H6Cl2N2O4S2
[MDL Number]

MFCD28138396
[MOL File]

1391054-76-4.mol
[Molecular Weight]

305.159
Chemical PropertiesBack Directory
[Melting point ]

>220°C (dec.)
[storage temp. ]

Refrigerator
[solubility ]

Chloroform (Slightly), DMSO (Slightly)
[form ]

Solid
[color ]

Light Brown
Hazard InformationBack Directory
[Uses]

Labelled Diclofenamide, a potent carbonic anhydrase inhibitor. Diclofenamide may provide a therapeutic strategy in the inhibition of the human cytosolic isoforms I and II and transmembrane tumor-assoc iated isoenzymes IX and XII. Diclofenamide has been shown to be is effective in the prevention of episodic weakness in both hypokalemic periodic paralysis (HypoPP) and potassium-sensitive periodic par alysis (PSPP).
[Uses]

Labelled Diclofenamide, a potent carbonic anhydrase inhibitor. Diclofenamide may provide a therapeutic strategy in the inhibition of the human cytosolic isoforms I and II and transmembrane tumor-associated isoenzymes IX and XII. Diclofenamide has been shown to be is effective in the prevention of episodic weakness in both hypokalemic periodic paralysis (HypoPP) and potassium-sensitive periodic paralysis (PSPP).
[in vivo]

Isotopic labels can non-invasively track the distribution, transformation and clearance of compounds and their metabolites in the body through techniques such as mass spectrometry (MS) and nuclear magnetic resonance (NMR), which is beneficial to the study of pharmacometabolic kinetics (ADME).
Isotope labeling can reveal specific steps in metabolic pathways. Using compounds with stable isotope labels at specific locations directly in humans or animal models can also help verify drug mechanisms and evaluate unexpected side effects, improving the accuracy and efficiency of clinical research[3].

[storage]

Store at -20°C
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