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1391449-26-5

1391449-26-5 Structure

1391449-26-5 Structure
IdentificationBack Directory
[Name]

ANTI-HUMAN SIRTUIN TYPE 3 (SIRT 3)
[CAS]

NoCAS
[Synonyms]

Sirt3
SIR2L3
mSIR2L3
sir2-like 3
Anti-SIR2L3
Anti-hSIRT3
Anti-HGNC:14931
Sirtuin 3 human
SIR2-like protein 3
Anti-Sirtuin 3 (S. cerevisiae)
SIRT3, active, GST tagged human
ANTI-HUMAN SIRTUIN TYPE 3 (SIRT 3)
NAD-dependent deacetylase sirtuin-3
Anti-SIRT3 antibody produced in rabbit
Anti-SIRT3 antibody produced in chicken
Anti-NAD-dependent deacetylase sirtuin-3
Silent mating type information regulation 2
Anti-SIRT3 (AB1) antibody produced in rabbit
Anti-SIRT3 (AB2) antibody produced in rabbit
Anti-Silent mating type information regulation 2
ANTI-MOUSE SIRT3 (C-TERM) antibody produced in rabbit
Mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase
Anti-Nicotinamide adenine dinucleotide-dependent deacetylase mitochondrial
sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae)
Anti-sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae)
[MDL Number]

MFCD07784765
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[form ]

buffered aqueous solution
[biological source]

rabbit
[Specific Activity]

123-196RLU/min·ng
[Major Application]

cell analysis
Safety DataBack Directory
[WGK Germany ]

WGK 1
[Storage Class]

10 - Combustible liquids
Hazard InformationBack Directory
[Uses]

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
[Biological Activity]

Sirtuin 3 (Sirt3) is mainly a nuclear protein th at transfers to the mitochondria during cellular stress. In humansSirt3 deacetylates and activates the mitochondrial enzyme acetyl-CoA synthetase 1 (AceCS2). Sirt3 is implicated in regulating mitochondrial function and thermogenesis in brown adipocytes. Its levels have been shown to correlate with extended life span. Increased levels of Sirt3 were associated with node positive breast cancer.
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