| Chemical Properties | Back Directory | [Boiling point ]
329.8±42.0 °C(Predicted) | [density ]
1.13±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [form ]
Solid | [pka]
8.79±0.35(Predicted) | [color ]
White to light yellow |
| Hazard Information | Back Directory | [Uses]
ME1111 is an antifungal agent that is active against dermatophytes. ME1111 is an inhibitor of the succinate dehydrogenase of Trichophyton species. ME1111 has an excellent ability to penetrate human nails and is used for onychomycosis research[1][2]. | [References]
[1] Nishiyama Y, et al. Morphological Effect of the New Antifungal Agent ME1111 on Hyphal Growth of Trichophyton mentagrophytes, Determined by Scanning and Transmission Electron Microscopy. Antimicrob Agents Chemother. 2016 Dec 27;61(1). DOI:10.1128/AAC.01195-16
[2] Takahata S, et al. Mechanism of Action of ME1111, a Novel Antifungal Agent for Topical Treatment of Onychomycosis. Antimicrob Agents Chemother. 2015 Nov 23;60(2):873-80. DOI:10.1128/AAC.01790-15 |
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