| Identification | Back Directory | [Name]
5-(7-Chloro-1H-indol-3-ylMethyl)-iMidazolidine-2,4-dione | [CAS]
1391980-92-9 | [Synonyms]
Necroptosis-IN-1
5-(7-Chloro-1H-indol-3-ylMethyl)-iMidazolidine-2,4-dione
2,4-Imidazolidinedione, 5-[(7-chloro-1H-indol-3-yl)methyl]-
NecroptosisIN1,RIP kinase,Inhibitor,inhibit,Necroptosis,RIPK,Necroptosis IN 1,Receptor-interacting protein kinases | [Molecular Formula]
C12H10ClN3O2 | [MDL Number]
MFCD32857163 | [MOL File]
1391980-92-9.mol | [Molecular Weight]
263.68 |
| Hazard Information | Back Directory | [Uses]
Necroptosis-IN-1, an analog of Necrostatin-1, is a potent necroptosis inhibitor. Necroptosis-IN-1 is a RIPK inhibitor[1]. | [References]
[1] Jenny L Maki, et al. Fluorescence polarization assay for inhibitors of the kinase domain of receptor interacting protein 1. Anal Biochem. 2012 Aug 15;427(2):164-74. DOI:10.1016/j.ab.2012.05.019 |
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