| Identification | Back Directory | [Name]
6-bromo-2,3-dihydrobenzofuran-3-ol | [CAS]
1392072-52-4 | [Synonyms]
6-bromo-2,3-dihydrobenzofuran-3-ol
6-BROMO-2,3-DIHYDROBENZOFUNAN-3-OL
3-Benzofuranol, 6-bromo-2,3-dihydro-
6-bromo-2,3-dihydro-1-benzofuran-3-ol | [Molecular Formula]
C8H7BrO2 | [MDL Number]
MFCD22574142 | [MOL File]
1392072-52-4.mol | [Molecular Weight]
215.04 |
| Chemical Properties | Back Directory | [Boiling point ]
295.0±40.0 °C(Predicted) | [density ]
1.752±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [pka]
13.09±0.20(Predicted) |
| Hazard Information | Back Directory | [Synthesis]
1. Synthesis of (racemic)-6-bromo-2,3-dihydrobenzofuran-3-ol
To a solution of 6-bromo-3-benzofuranone (10.5 g, 49.28 mmol) in methanol (100 mL) was slowly added sodium borohydride (2.37 g, 64.07 mmol) at 0 °C. Subsequently, the reaction mixture was stirred at room temperature for 2 hours. Upon completion of the reaction, the reaction was quenched with saturated ammonium chloride solution (50 mL) and extracted twice with ethyl acetate (2 x 50 mL). The organic phases were combined, dried over anhydrous sodium sulfate and concentrated under reduced pressure to give the product 6-bromo-2,3-dihydrobenzofuran-3-ol (9.75 g, 92% yield) as a colorless liquid. | [References]
[1] Patent: WO2012/101011, 2012, A2. Location in patent: Page/Page column 56
[2] Patent: US2013/18055, 2013, A1. Location in patent: Paragraph 0331-0332 |
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Bide Pharmatech Ltd.
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Xi 'an fanta biotechnology co., LTD
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19929974101 //1144079830; 19929974101 |
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https://www.chemicalbook.com/ShowSupplierProductsList30720/0_EN.htm |
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