| Identification | Back Directory | [Name]
13,14-dihydro-15-keto Prostaglandin D1 Exclusive | [CAS]
1392219-79-2 | [Synonyms]
WTCAXDJXNVRHRC-KURKYZTESA-N
Prostanoic acid, 9-hydroxy-11,15-dioxo-, (9α)-
13,14-dihydro-15-keto Prostaglandin D1 Exclusive | [Molecular Formula]
C20H34O5 | [MDL Number]
MFCD11045842 | [MOL File]
1392219-79-2.mol | [Molecular Weight]
354.49 |
| Chemical Properties | Back Directory | [Boiling point ]
537.2±35.0 °C(Predicted) | [density ]
1.072±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 50 mg/ml; DMSO: 30 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 2 mg/ml | [pka]
4.78±0.10(Predicted) |
| Hazard Information | Back Directory | [Description]
Prostaglandin D1 (PGD1) is the theoretical D-series metabolite of dihomo-γ-linolenic acid (DGLA), but to date it has not been isolated as a natural product. It is an inhibitor of ADP-induced platelet aggregation in humans with an IC50 value of 320 ng/ml, about 1/10 as potent as PGD2. 13,14-dihydro-15-keto Prostaglandin D1 (13,14-dihydro-15-keto PGD1) is the theoretical metabolite of PGD1 via the 15-hydroxy PG dehydrogenase metabolic pathway. No biological studies for this compound have been reported. | [Uses]
13,14-Dihydro-15-keto prostaglandin D1 is a derivative of prostaglandin D1[1]. | [Definition]
ChEBI: 13,14-dihydro-15-keto Prostaglandin D1 is a prostanoid. | [References]
[1] Amagai Y, et al. Dihomo-γ-linolenic acid prevents the development of atopic dermatitis through prostaglandin D1 production in NC/Tnd mice. J Dermatol Sci. 2015 Jul;79(1):30-7. DOI:10.1016/j.jdermsci.2015.03.010 |
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