| Identification | Back Directory | [Name]
Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 trifluoroacetate | [CAS]
1392300-20-7 | [Synonyms]
Mca-KPLGL-Dap(Dnp)-AR-NH2 TFA
Mca-KPLGL-Dap(Dnp)-AR-NH2 (trifluoroacetate salt)
Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 trifluoroacetate | [MDL Number]
MFCD07368601 |
| Hazard Information | Back Directory | [Uses]
Mca-KPLGL-Dap(Dnp)-AR-NH2 TFA is a fluorogenic substrate for matrix metalloproteinases (MMPs). 7-methoxycoumarin-4 acetyl (Mac) is released and its fluorescence can be used to quantify MMP activity. Mac displays Ex/Em of 328/420 nm[1]. | [References]
[1] Ulf Neumann, et al. Characterization of Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2, a fluorogenic substrate with increased specificity constants for collagenases and tumor necrosis factor converting enzyme. Comparative Study Anal Biochem. 2004 May 15;328(2):166-73. DOI:10.1016/j.ab.2003.12.035 |
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