| Identification | Back Directory | [Name]
N-ACETYL-S-GERANYLGERANYL-L-CYSTEINE | [CAS]
139332-94-8 | [Synonyms]
AGGC
PKFBJSDMCRJYDC-GEZSXCAASA-N
N-ACETYL-S-GERANYLGERANYL-L-CYSTEINE
N-Acetyl-S-geranylgeranyl-L-cysteine (AGGC)
N-ACETYL-S-GERANYLGERANYL-L-CYSTEINE USP/EP/BP
N-ACETYL-S-(3,7,11,15-TETRAMETHYL-2E,6E,10E,14-HEXADECATETRAENYL)-L-CYSTEINE
AGGC, N-Acetyl-S-(3,7,11,15-tetramethyl-2E,6E,10E,14-hexadecatetraenyl)-L-cysteine
2-acetamido-3-(3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraenylsulfanyl)propanoicaci
L-Cysteine, N-acetyl-S-[(2E,6E,10E)-3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraen-1-yl]-
(R)-2-Acetamido-3-(((2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-yl)thio)propanoic acid | [EINECS(EC#)]
200-578-6 | [Molecular Formula]
C25H41NO3S | [MDL Number]
MFCD00216147 | [MOL File]
139332-94-8.mol | [Molecular Weight]
435.66 |
| Chemical Properties | Back Directory | [Boiling point ]
617.5±55.0 °C(Predicted) | [density ]
1.013±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C | [solubility ]
0.1 M Na2CO3: 11 mg/ml; DMF: 50 mg/ml; DMSO: 33 mg/ml; Ethanol: 50 mg/ml | [form ]
ethanol solution | [pka]
3.31±0.10(Predicted) |
| Hazard Information | Back Directory | [Description]
N-acetyl-S-geranylgeranyl-L-Cysteine is a synthetic substrate for the isoprenylated protein methyltransferase (also known as S-adenosylmethionine-dependent methyltransferase). Because it is able to serve as a substrate for the methyltransferase, it effectively functions as an inhibitor of methylation of endogenous isoprenylated proteins. | [Uses]
N-acetyl-S-geranylgeranyl-L-Cysteine is a synthetic substrate for the isoprenylated protein methyltransferase (also known as S-adenosylmethionine-dependent methyltransferase). Because it is able to serve as a substrate for the methyltransferase, it effectively functions as an inhibitor of methylation of endogenous isoprenylated proteins. | [Definition]
ChEBI: N-acetyl-s-geranylgeranyl-l-cysteine is a diterpenoid. | [storage]
Store at -20°C | [References]
[1] CRAIG VOLKER. A single activity carboxyl methylates both farnesyl and geranylgeranyl cysteine residues[J]. FEBS Letters, 1991, 295 1: Pages 189-194. DOI: 10.1016/0014-5793(91)81415-5
[2] D PéREZ-SALA. Prenylated protein methyltransferases do not distinguish between farnesylated and geranylgeranylated substrates.[J]. Biochemical Journal, 1992, 284 ( Pt 3): 835-840. DOI: 10.1042/bj2840835 |
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BOC Sciences
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https://www.bocsci.com |
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Enzo Biochem Inc
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Enzo Biochem Inc. 13797054060 |
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www.enzo.com |
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Abcam Limited
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021-2070050 400921018 |
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www.abcam.cn |
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