ChemicalBook--->CAS DataBase List--->1393441-53-6

1393441-53-6

1393441-53-6 Structure

1393441-53-6 Structure
IdentificationBack Directory
[Name]

RY796
[CAS]

1393441-53-6
[Synonyms]

RY796
2-(DIMETHYLAMINO)-5-[(2-METHYL-1-OXOPROPYL)AMINO]-N-[(1R)-1-PHENYLETHYL]-BENZAMIDE
[Molecular Formula]

C21H27N3O2
[MDL Number]

MFCD28160786
[MOL File]

1393441-53-6.mol
[Molecular Weight]

353.46
Chemical PropertiesBack Directory
[Boiling point ]

561.0±50.0 °C(Predicted)
[density ]

1.132±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[form ]

Solid
[pka]

13.95±0.46(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

RY796 is a potent and selective voltage-gated potassium (KV2) channel inhibitor with IC50s of 0.25 μM and 0.09 μM for KV2.1 and KV2.2. RY796 has analgesic activity[1].
[Biological Activity]

RY796 is a potent and selective voltage-gated potassium (KV2) channel inhibitor with IC50s of 0.25 μM and 0.09 μM for KV2.1 and KV2.2. RY796 has analgesic activity[1].
[References]

[1]. Herrington J, et al. Identification of novel and selective Kv2 channel inhibitors. Mol Pharmacol. 2011 Dec;80(6):959-64.
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