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1393748-80-5

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1393748-80-5 Structure

1393748-80-5 Structure
IdentificationBack Directory
[Name]

3-(3-Methoxyphenyl)-2-Methyl-N-(2-(thiazol-4-yl)-1H-benzo[d]iMidazol-5-yl)propanaMide hydrochloride
[CAS]

1393748-80-5
[Synonyms]

RY785
Na+ channels,inhibit,RY785,Sodium Channel,RY-785,Na channels,RY 785,Inhibitor
Benzenepropanamide, 3-methoxy-α-methyl-N-[2-(4-thiazolyl)-1H-benzimidazol-6-yl]-
3-(3-Methoxyphenyl)-2-Methyl-N-(2-(thiazol-4-yl)-1H-benzo[d]iMidazol-5-yl)propanaMide hydrochloride
[Molecular Formula]

C21H21ClN4O2S
[MDL Number]

MFCD27977269
[MOL File]

1393748-80-5.mol
[Molecular Weight]

428.935
Chemical PropertiesBack Directory
[density ]

1.333±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 20 mg/ml; DMSO: 15 mg/ml; Ethanol: 15 mg/ml
[form ]

A crystalline solid
[pka]

9.81±0.10(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Description]

RY785 is a selective inhibitor of Kv2.1 voltage-gated potassium channels (IC50 = 0.05 μM) that does not affect Cav2 calcium channels. It displays over 100-fold selectivity for Kv2.1 over Cav1.2 (IC50 = 17 μM).
Spectrum DetailBack Directory
[Spectrum Detail]

3-(3-Methoxyphenyl)-2-Methyl-N-(2-(thiazol-4-yl)-1H-benzo[d]iMidazol-5-yl)propanaMide hydrochloride(1393748-80-5)1HNMR
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