| Identification | Back Directory | [Name]
8α-Hydroxyhirsutinolide | [CAS]
1394156-45-6 | [Synonyms]
8α-Hydroxyhirsutinolide
8α-Hydroxyhirsutinolide
8alpha-Hydroxyhirsutinolide
(4S,6R,7S,10R,11E)-5,6,7,8,9,10-Hexahydro-4,7-dihydroxy-3-(hydroxymethyl)-6,10-dimethyl-7,10-epoxycyclodeca[b]furan-2(4H)-one
7,10-Epoxycyclodeca[b]furan-2(4H)-one, 5,6,7,8,9,10-hexahydro-4,7-dihydroxy-3-(hydroxymethyl)-6,10-dimethyl-, (4S,6R,7S,10R,11E)- | [Molecular Formula]
C15H20O6 | [MDL Number]
MFCD32645033 | [MOL File]
1394156-45-6.mol | [Molecular Weight]
296.32 |
| Hazard Information | Back Directory | [Uses]
8α-Hydroxyhirsutinolide is a sesquiterpene lactone. 8α-Hydroxyhirsutinolide inhibits TNF-α-induced NF-κB activity (IC50: 1.9 μM) and NO production. 8α-Hydroxyhirsutinolide can be isolated from Vernonia cinerea[1]. | [References]
[1] Youn UJ, et al. Anti-inflammatory sesquiterpene lactones from the flower of Vernonia cinerea. Bioorg Med Chem Lett. 2012 Sep 1;22(17):5559-62. DOI:10.1016/j.bmcl.2012.07.010 |
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