| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [form ]
Powder | [Water Solubility ]
Soluble to 1 mg/ml in water | [Sequence]
Gly-Tyr-Cys-Ala-Glu-Lys-Gly-Ile-Arg-Cys-Asp-Asp-Ile-His-Cys-Cys-Thr-Gly-Leu-Lys-Cys-Lys-Cys-Asn-Ala-Ser-Gly-Tyr-Asn-Cys-Val-Cys-Arg-Lys-Lys-NH2 (Disulfide bridge: Cys3-Cys16, Cys10-Cys21, Cys15-Cys32, Cys23-Cys30) |
| Hazard Information | Back Directory | [Description]
Potent P2X3 receptor modulator (IC50 = 12 nM). Exhibits negligible effects on P2X2 and P2X2/3. Demonstrates antinociceptive properties in an animal model of inflammatory pain. | [Uses]
Purotoxin 1 is a P2X3 receptor inhibitor. Purotoxin 1 shows antinociceptive properties in animal models of inflammatory pain. Purotoxin 1 can be isolated from the venom of the wolf spider Geolycosa sp[1]. | [References]
[1] Grishin EV, et al. Novel peptide from spider venom inhibits P2X3 receptors and inflammatory pain. Ann Neurol. 2010 May;67(5):680-3. DOI:10.1002/ana.21949 |
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| Company Name: |
Enzo Biochem Inc
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| Tel: |
Enzo Biochem Inc. 13797054060 |
| Website: |
www.enzo.com |
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