| Identification | Back Directory | [Name]
2’-Deoxy-2’-fluoro-3’,5’-bis-O-TBDMS-uridine | [CAS]
139878-36-7 | [Synonyms]
2’-Deoxy-2’-fluoro-3’,5’-bis-O-TBDMS-uridine
2’-Deoxy-2’-fluoro-3’,5’-bis-O-TBDMS-uridine
Uridine, 2'-deoxy-3',5'-bis-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-fluoro- | [Molecular Formula]
C21H39FN2O5Si2 | [MOL File]
139878-36-7.mol | [Molecular Weight]
474.71 |
| Hazard Information | Back Directory | [Uses]
2’-Deoxy-2’-fluoro-3’,5’-bis-O-TBDMS-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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