| Identification | Back Directory | [Name]
bas 320i | [CAS]
139968-49-3 | [Synonyms]
BAS3201
bas 320i
METAFLUMIZONE
Metaflumizone-d6
Metaflumizone [iso]
metaflumizone (bsi, pa iso)
Metaflumizone@100 μg/mL in Acetonitrile
Metaflumizone Solution in Acetonitrile, 100μg/mL
2μ-[2-(4-Cyanophenyl)-1-(α,α,α-trifluoro-m-tolyl)ethylidene]-4-(trifluoromethoxy)carbanilohydrazide
2-[2-(4-Cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]-N-[4-(trifluoromethoxy)phenyl]-hydrazinecarboxamide
Hydrazinecarboxamide,2-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]-N-[4-(trifluoromethoxy)phenyl]- | [EINECS(EC#)]
204-798-3 | [Molecular Formula]
C24H16F6N4O2 | [MDL Number]
MFCD08690508 | [MOL File]
139968-49-3.mol | [Molecular Weight]
506.404 |
| Safety Data | Back Directory | [RIDADR ]
UN 3077 9 / PGIII | [WGK Germany ]
WGK 3 | [RTECS ]
MV1576452 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Lact.
Repr. 2
STOT RE 2 |
| Hazard Information | Back Directory | [Description]
Metaflumizone is a semicarbazone broad-spectrum insecticide. It has a low aqueous solubility, is non-volatile and a low potential for leaching to groundwater based on its chemical properties. It is persistent in soil and in water-sediment systems. It has a low mammalian toxicity and considered to have potential negative reproduction/developmental effects. It also has a high potential for bioaccumulation. It has a low to moderate toxicity to most birds, aquatic species, honeybees and earthworms. | [Chemical Properties]
Metaflumizone technical product appears as a white crystalline powder with a faint aromatic odor. Metaflumizone is a semicarbazone insecticide with low toxicity, environmental friendliness, and a low-risk systemic action. | [Uses]
Metaflumizone is a semicarbazone insecticide that works by blocking sodium channel in target insects resulting in paralyzation associated with blocking nerve activity. Metaflumizone is useful as a hea rtworm control treatment.
| [Production Methods]
Metaflumizone is synthesised through a condensation reaction involving two key intermediates: m-trifluoromethylphenyl-4-nitrilebenzylketone and p-trifluoromethoxyphenylaminohydrazide. These compounds are combined in a reactor with a water-insoluble organic solvent and a suitable catalyst, then heated to temperatures between 80 DegC and 140 DegC for 1 to 3 hours. During the reaction, water is generated and removed by the solvent, which drives the reaction forward and improves yield. After completion, the mixture is cooled to between 0 and 30 DegC, and the product is isolated by filtration. | [Mechanism of action]
Broad-spectrum, attacks insect nervous system causing paralysis. Voltage-dependent sodium channel modulator. | [Veterinary Drugs and Treatments]
Metaflumizone is a new insecticide used for the treatment and control of fleas on dogs and cats. It blocks the influx of sodium required
to propagate a nerve impulse along the axon and dendrite of the neuron causing a reduction in feeding, loss of coordination, paralysis
and death of the flea. | [storage]
Store at -20°C | [Pesticide Type]
Insecticide; Veterinary substance |
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