| Identification | Back Directory | [Name]
Colby trifluoromethylation reagent | [CAS]
1400691-55-5 | [Synonyms]
Colby trifluoromethylation reagent
Hexafluoroacetone hydrate-1,8-diazo-bicyclo[5.4.0]undec-7-ene salt
Hexafluoroacetone hydrate-1,8-diazo-bicyclo[5.4.0]undec-7-ene salt AldrichCPR
1,1,1,3,3,3-Hexafluoropropane-2,2-diol-1,8-diazo-bicyclo[5.4.0]undec-7-ene salt | [Molecular Formula]
C12H18F6N2O2 | [MDL Number]
MFCD22417241 | [MOL File]
1400691-55-5.mol | [Molecular Weight]
336.28 |
| Safety Data | Back Directory | [WGK Germany ]
WGK 3 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral
Eye Dam. 1 |
| Hazard Information | Back Directory | [Uses]
The Colby Trifluoromethylation Reagent is an air-stable, white solid, which can be used as a source of fluoroform through the release of trifluoroacetate. This reagent can add trifluoromethyl groups in a nucleophlic fashion to carbonyls and sulfides. | [General Description]
Colby trifluoromethylation reagent is an amidinate salt of hexafluoroacetone hydrate. This reagent can be prepared from the ethereal solution of hexafluoroacetone trihydrate. It undergoes various trifluoromethylation reactions with electrophiles under different reaction conditions to afford trifluoromethylated products. |
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