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14007-64-8

14007-64-8 Structure

14007-64-8 Structure
IdentificationBack Directory
[Name]

butetamate
[CAS]

14007-64-8
[Synonyms]

butetamate
Butetamato
Butethamate
CKWHSYRZDLWQFV-UHFFFAOYSA-N
2-(diethylamino)ethyl 2-phenylbutanoate
Butethamate (base and/or unspecified salts)
2-phenyl-butyric acid-(2-diethylamino-ethyl ester)
Benzeneacetic acid, α-ethyl-, 2-(diethylamino)ethyl ester
[EINECS(EC#)]

237-817-9
[Molecular Formula]

C16H25NO2
[MOL File]

14007-64-8.mol
[Molecular Weight]

263.38
Chemical PropertiesBack Directory
[Boiling point ]

bp11 167-169°
[density ]

0.9903 (rough estimate)
[refractive index ]

nD20 1.4909
[pka]

9.22±0.25(Predicted)
Hazard InformationBack Directory
[Originator]

Butetamat-dihydrogencitrat,Chemische Werke Hommel GmbH and Co.KG
[Definition]

ChEBI: Butetamate is an alkylbenzene.
[Manufacturing Process]

16.4 parts of alpha-phenylbutiric acid, 17.5 parts of beta-diethylaminoethylchloride hydrochloride and 35 parts of dry potassium carbonate in 60 parts diisopropyl ether was stirred for 18 hours under reflux. To the reaction mixture at 40°C was added 120 parts of the water. Organic layer was washed with the water. The solvent was removed and the 2- (diethylamino)ethyl-2-phenylbutyrate was distilled at 167-168°C/10 mm; melting point of hydrochloride 167-169°C.
In practice it is usually used as citrate.
[Therapeutic Function]

Anticholinergic, Spasmolytic, Antitussive
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