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1403406-29-0

1403406-29-0 Structure

1403406-29-0 Structure
IdentificationBack Directory
[Name]

IONIS PTP1BRx
[CAS]

1403406-29-0
[Synonyms]

IONIS PTP1BRx
Hazard InformationBack Directory
[Uses]

IONIS PTP1BRx (ISIS 404173) is an antisense inhibitor of protein tyrosine phosphatase 1B (PTP-1B). IONIS PTP1BRx shows antidiabetic activity, and can be used for the study of insulin resistance and type 2 diabetes mellitus associated with obesity[1].
[References]

[1] Stanley T Crooke, et al. The Effects of 2'-O-Methoxyethyl Oligonucleotides on Renal Function in Humans. Nucleic Acid Ther. 2018 Feb;28(1):10-22. DOI:10.1089/nat.2017.0693
1403406-29-0 suppliers list
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