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140626-94-4

140626-94-4 Structure

140626-94-4 Structure
IdentificationBack Directory
[Name]

matlystatin A
[CAS]

140626-94-4
[Synonyms]

Matlystatin
matlystatin A
[Molecular Formula]

C27H47N5O8S
[MDL Number]

MFCD00912518
[MOL File]

140626-94-4.mol
[Molecular Weight]

601.761
Hazard InformationBack Directory
[Description]

Matlystatin A is an aminopeptidase inhibitor. It expresses multiple inhibitory activity against both aminopeptidase N and matrix metalloproteinases (MMP).
[Uses]

Matlystatin A is a potent aminopeptidase inhibitor, with IC50 values of 0.3 μM and 0.56 μM against 92 kDa and 72 kDa type IV collagenases, respectively. Matlystatin A can be utilized in cancer research[1].
[References]

[1] Tanzawa K, et al. Matlystatins, new inhibitors of typeIV collagenases from Actinomadura atramentaria. II. Biological activities. J Antibiot (Tokyo). 1992 Nov;45(11):1733-7. DOI:10.7164/antibiotics.45.1733
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