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140646-80-6

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140646-80-6 Structure

140646-80-6 Structure
IdentificationBack Directory
[Name]

MCI 826
[CAS]

140646-80-6
[Synonyms]

MCI 826
Biricodar (VX-710)
Butanoic acid, 2,2-diethyl-4-[[3-[(1E)-2-[4-(1-methylethyl)-2-thiazolyl]ethenyl]phenyl]amino]-4-oxo-
[Molecular Formula]

C22H28N2O3S
[MDL Number]

MFCD00874532
[MOL File]

140646-80-6.mol
[Molecular Weight]

400.53
Chemical PropertiesBack Directory
[density ]

1.205±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[pka]

4.76±0.15(Predicted)
Hazard InformationBack Directory
[Uses]

MCI826 is a P-glycoprotein (P-gp) antagonist.
[References]

[1] Morad SA, et al. Tamoxifen magnifies therapeutic impact of ceramide in human colorectal cancer cells independent of p53. Biochem Pharmacol. 2013 Apr 15;85(8):1057-65. DOI:10.1016/j.bcp.2013.01.015
Spectrum DetailBack Directory
[Spectrum Detail]

MCI 826(140646-80-6)1HNMR
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