| Identification | Back Directory | [Name]
5-Heptenoic acid, 7-[(1R,2R,3R)-3-hydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]-5-oxocyclopentyl]-, 1-methylethyl ester, (5Z)- | [CAS]
141074-06-8 | [Synonyms]
9-keto Latanoprost
5-Heptenoic acid, 7-[(1R,2R,3R)-3-hydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]-5-oxocyclopentyl]-, 1-methylethyl ester, (5Z)- | [Molecular Formula]
C26H38O5 | [MOL File]
141074-06-8.mol | [Molecular Weight]
430.58 |
| Chemical Properties | Back Directory | [Boiling point ]
579.6±50.0 °C(Predicted) | [density ]
1.090±0.06 g/cm3(Predicted) | [solubility ]
DMF: 100 mg/ml
DMSO: 100 mg/ml
DMSO: PBS(pH 7.2) (1:2): 80 µg/ml
Ethanol: 100 mg/ml | [pka]
14.06±0.60(Predicted) |
| Hazard Information | Back Directory | [Uses]
9-keto latanoprost is a derivative of the F-prostaglandin (FP) receptor agonist Latanoprost (HY-B0577)[1]. | [References]
[1] Pauly A, et al. In vitro and in vivo comparative toxicological study of a new preservative-free latanoprost formulation. Invest Ophthalmol Vis Sci. 2012 Dec 13;53(13):8172-80. DOI:10.1167/iovs.12-10766 |
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