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1411976-18-5

1411976-18-5 Structure

1411976-18-5 Structure
IdentificationBack Directory
[Name]

P110
[CAS]

1411976-18-5
[Synonyms]

[Molecular Formula]

C32H56N10O11
[MOL File]

1411976-18-5.mol
[Molecular Weight]

756.85
Chemical PropertiesBack Directory
[density ]

1.47±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[form ]

Solid
[pka]

3.01±0.10(predicted)
[color ]

White to off-white
[Sequence]

Asp-Leu-Leu-Pro-Arg-Gly-Ser
Hazard InformationBack Directory
[Uses]

P110 heptapeptide, a peptide inhibitor of Drp1-Fis1 interaction, reduces pathology in numerous models of neurodegeneration, ischemia, and sepsis without blocking the physiological functions of Drp1[1].
[References]

[1] Luis Rios, et al. Targeting an allosteric site in dynamin-related protein 1 to inhibit Fis1-mediated mitochondrial dysfunction. Nat Commun. 2023 Jul 19;14(1):4356. DOI:10.1038/s41467-023-40043-0
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