ChemicalBook--->CAS DataBase List--->141237-50-5

141237-50-5

141237-50-5 Structure

141237-50-5 Structure
IdentificationBack Directory
[Name]

HIV-1 REV PROTEIN (34-50)
[CAS]

141237-50-5
[Synonyms]

HIV-1 rev Protein
HIV-1 REV PROTEIN (34-50)
Rev protein(Human immunodeficiency virus 1 fragment)
THR-ARG-GLN-ALA-ARG-ARG-ASN-ARG-ARG-ARG-ARG-TRP-ARG-GLU-ARG-GLN-ARG
H-THR-ARG-GLN-ALA-ARG-ARG-ASN-ARG-ARG-ARG-ARG-TRP-ARG-GLU-ARG-GLN-ARG-OH
L-Arginine, L-threonyl-L-arginyl-L-glutaminyl-L-alanyl-L-arginyl-L-arginyl-L-asparaginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-tryptophyl-L-arginyl-L-α-glutamyl-L-arginyl-L-glutaminyl-
[Molecular Formula]

C97H173N51O24
[MDL Number]

MFCD00214622
[MOL File]

141237-50-5.mol
[Molecular Weight]

2437.74
Chemical PropertiesBack Directory
[storage temp. ]

-15°C
[solubility ]

Soluble in DMSO
[Sequence]

Thr-Arg-Gln-Ala-Arg-Arg-Asn-Arg-Arg-Arg-Arg-Trp-Arg-Glu-Arg-Gln-Arg
Hazard InformationBack Directory
[Uses]

HIV-1 Rev (34-50) is a 17-aa peptide derived from the Rev-responsive element (RRE)-binding domains of Rev in HIV-1, with anti-HIV-1 activity.
[IC 50]

HIV-1
[References]

[1] Shimane K, et al. Rev-derived peptides inhibit HIV-1 replication by antagonism of Rev and a co-receptor, CXCR4. Int J Biochem Cell Biol. 2010 Sep;42(9):1482-8. DOI:10.1016/j.biocel.2010.05.005
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