| Identification | Back Directory | [Name]
L-Argininamide, L-isoleucyl-L-seryl-L-glutaminyl-L-alanyl-L-valyl-L-histidyl-L-alanyl-L-alanyl-L-histidyl-L-alanyl-L-α-glutamyl-L-isoleucyl-L-asparaginyl-L-α-glutamyl-L-alanylglycyl- | [CAS]
141312-45-0 | [Synonyms]
L-Argininamide, L-isoleucyl-L-seryl-L-glutaminyl-L-alanyl-L-valyl-L-histidyl-L-alanyl-L-alanyl-L-histidyl-L-alanyl-L-α-glutamyl-L-isoleucyl-L-asparaginyl-L-α-glutamyl-L-alanylglycyl- | [Molecular Formula]
C74H121N27O24 | [MOL File]
141312-45-0.mol | [Molecular Weight]
1772.92 |
| Hazard Information | Back Directory | [Uses]
OVA peptide mainly exists in egg white, it is a class I (Kb)-restricted peptide epitope of ovalbumin presented by the class I MHC (major histocompatibility complex) molecule, H-2Kb (class I genes of the mouse MHC). OVA peptide has been widely studied in allergy research[1][2]. | [in vivo]
OVA peptide with bone marrow-generated DC pulse are potent inducers of OVA-specific CTL responses in vivo, compared with splenocytes or RMA-S cells pulsed with OVA peptide, or compared with immunization with free OVA peptide mixed with adjuvant[2]. | [References]
[1] Zhu L, et al. Alginate Particles with Ovalbumin (OVA) Peptide Can Serve as a Carrier and Adjuvant for Immune Therapy in B16-OVA Cancer Model. Med Sci Monit Basic Res. 2017 Apr 28;23:166-172. DOI:10.12659/msmbr.901576
[2] Porgador A, Gilboa E. Bone marrow-generated dendritic cells pulsed with a class I-restricted peptide are potent inducers of cytotoxic T lymphocytes. J Exp Med. 1995 Jul 1;182(1):255-60. DOI:10.1084/jem.182.1.255 |
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