| Identification | Back Directory | [Name]
27-ethyl-14,16,18,20,24,26-hexahydroxy-2,3,15-trimethyl-1-oxacyclooctacosa-4,6,8,10,12- pentaen-28-one | [CAS]
141443-40-5 | [Synonyms]
AB023b
27-ethyl-14,16,18,20,24,26-hexahydroxy-2,3,15-trimethyl-1-oxacyclooctacosa-4,6,8,10,12- pentaen-28-one | [Molecular Formula]
C32H52O8 | [MOL File]
141443-40-5.mol | [Molecular Weight]
564.75 |
| Hazard Information | Back Directory | [Description]
AB023b is an antibiotic that displays antifungal properties. | [Uses]
Antibiotic AB023b is part of macrocyclic pentaene antibiotic complex, forming the main components with Antibiotic AB023a (HY-137084). Antibiotic AB023b exhibits antifungal activity against Candida albicans, and plant pathogenic fungi, Botrytis cinerea, Fusarium moniliforme and Pythium ultimum[1][2]. | [References]
[1] Bortolo R, et al., AB023, novel polyene antibiotics. II. Isolation and structure determination. J Antibiot (Tokyo). 1993 Feb;46(2):255-64. DOI:10.7164/antibiotics.46.255
[2] Cidaria D, et al., AB023, novel polyene antibiotics. I. Taxonomy of the producing organism, fermentation and antifungal activity. J Antibiot (Tokyo). 1993 Feb;46(2):251-4. DOI:10.7164/antibiotics.46.251 |
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