ChemicalBook--->CAS DataBase List--->1415039-79-0

1415039-79-0

1415039-79-0 Structure

1415039-79-0 Structure
IdentificationBack Directory
[Name]

Phoenixin-14
[CAS]

1415039-79-0
[Synonyms]

Phoenixin-14
[Molecular Formula]

C75H110N18O20
[MOL File]

1415039-79-0.mol
[Molecular Weight]

1583.79
Chemical PropertiesBack Directory
[Boiling point ]

1897.158±65.00 °C(Press: 760.00 Torr)(predicted)
[density ]

1.339±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[form ]

Solid
[pka]

3.709±0.10(predicted)
[color ]

White to off-white
[Sequence]

Asp-Val-Gln-Pro-Pro-Gly-Leu-Lys-Val-Trp-Ser-Asp-Pro-Phe-NH2
Hazard InformationBack Directory
[Uses]

Phoenixin-14 (PNX-14) is one of the endogenous active isoform, and generates anxiolytic effect via the activation of the AHA GnRH system in mice. Phoenixin-14 inhibits ischemia/reperfusion-induced cytotoxicity in microglia[1][2].
[References]

[1] Jiang JH, et al. Effects of Phoenixin-14 on anxiolytic-like behavior in mice. Behav Brain Res. 2015;286:39-48. DOI:10.1016/j.bbr.2015.02.011
[2] Ma H, et al. Phoenixin 14 inhibits ischemia/reperfusion-induced cytotoxicity in microglia. Arch Biochem Biophys. 2020;689:108411. DOI:10.1016/j.abb.2020.108411
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