| Identification | Back Directory | [Name]
2-Pyrrolidinepropanoic acid, 1-[(3R,4S,5S)-4-[[(2S)-2-[[(1,1-dimethylethoxy)carbonyl]amino]-3-methyl-1-oxobutyl]methylamino]-3-methoxy-5-methyl-1-oxoheptyl]-β-methoxy-α-methyl-, (αR,βR,2S)- | [CAS]
1415246-54-6 | [Synonyms]
2-Pyrrolidinepropanoic acid, 1-[(3R,4S,5S)-4-[[(2S)-2-[[(1,1-dimethylethoxy)carbonyl]amino]-3-methyl-1-oxobutyl]methylamino]-3-methoxy-5-methyl-1-oxoheptyl]-β-methoxy-α-methyl-, (αR,βR,2S)- | [Molecular Formula]
C29H53N3O8 | [MOL File]
1415246-54-6.mol | [Molecular Weight]
571.75 |
| Chemical Properties | Back Directory | [Boiling point ]
704.4±60.0 °C(Predicted) | [density ]
1.100±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
4.27±0.11(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Boc-Val-Dil-Dap-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. | [IC 50]
Cleavable Linker | [References]
[1] Céline Mordant, et al. Total synthesis of dolastatin 10 through ruthenium-catalyzed asymmetric hydrogenations. Tetrahedron. Volume 63, Issue 27, 2 July 2007, Pages 6115-6123. |
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