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1415321-54-8

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1415321-54-8 Structure

1415321-54-8 Structure
IdentificationBack Directory
[Name]

Propanoic acid, 2-[3-[[5-[[[(1S)-1-[4-(1,1-dimethylethyl)phenyl]ethyl]amino]carbonyl]-2,3-dimethyl-1H-indol-1-yl]methyl]phenoxy]-2-methyl-
[CAS]

1415321-54-8
[Synonyms]

Propanoic acid, 2-[3-[[5-[[[(1S)-1-[4-(1,1-dimethylethyl)phenyl]ethyl]amino]carbonyl]-2,3-dimethyl-1H-indol-1-yl]methyl]phenoxy]-2-methyl-
[Molecular Formula]

C34H40N2O4
[MOL File]

1415321-54-8.mol
[Molecular Weight]

540.69
Chemical PropertiesBack Directory
[Boiling point ]

760.1±60.0 °C(Predicted)
[density ]

1.12±0.1 g/cm3(Predicted)
[pka]

3.27±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

Anticancer agent 183 (example 48) is a non-agonistic PPARG modulator. Anticancer agent 183 has a high affinity to PPARG (PPARγ). Anticancer agent 183 inhibits kinase-mediated phosphorylation of PPARG. Anticancer agent 183 can used for research on metabolic diseases to avoid side effects[1].
[IC 50]

PPAR-γ
[References]

[1] Theodore Mark Kamenecka, et al. N-benzylindole modulators of pparg. 2012.
1415321-54-8 suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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