| Identification | Back Directory | [Name]
(1S,5S,8AS,8BR)-1-[(1R)-1-HYDROXYETHYL]-5-METHOXY-2-OXO-1H,2H,5H,6H,7H,8H,8AH,8BH-AZETO[2,1-A]ISOINDOLE-4-CARBOXYLATE | [CAS]
141611-76-9 | [Synonyms]
Sanfetrinem sodium
(1S,5S,8AS,8BR)-1-[(1R)-1-HYDROXYETHYL]-5-METHOXY-2-OXO-1H,2H,5H,6H,7H,8H,8AH,8BH-AZETO[2,1-A]ISOINDOLE-4-CARBOXYLATE | [EINECS(EC#)]
827-423-0 | [Molecular Formula]
C14H18NO5- | [MOL File]
141611-76-9.mol | [Molecular Weight]
280.296 |
| Hazard Information | Back Directory | [Uses]
Sanfetrinem (GV104326) sodium is a beta-lactamase-stable antibiotic. Sanfetrinem sodium has broad-spectrum activity against gram-positive and gram-negative bacteria[1]. | [IC 50]
β-lactam | [References]
[1] Betriu C, et al. Activities of new antimicrobial agents (trovafloxacin, moxifloxacin, sanfetrinem, and quinupristin-dalfopristin) against Bacteroides fragilis group: comparison with the activities of 14 other agents. Antimicrob Agents Chemother. 1999 Sep;43(9):2320-2. DOI:10.1128/AAC.43.9.2320
[2] Tamura S, et al. In vivo antibacterial activities of sanfetrinem cilexetil, a new oral tricyclic antibiotic. Antimicrob Agents Chemother. 1998 Jul;42(7):1858-61. DOI:10.1128/AAC.42.7.1858 |
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