| Identification | Back Directory | [Name]
3,3'-((2-amino-2-((2-carboxyethoxy)methyl)propane-1,3-diyl)bis(oxy))dipropanoic acid hydrochloride | [CAS]
1416771-72-6 | [Synonyms]
Propanoic acid, 3,3'-[[2-amino-2-[(2-carboxyethoxy)methyl]-1,3-propanediyl]bis(oxy)]bis-, HCl
3,3'-((2-amino-2-((2-carboxyethoxy)methyl)propane-1,3-diyl)bis(oxy))dipropanoic acid hydrochloride | [Molecular Formula]
C13H24ClNO9 | [MOL File]
1416771-72-6.mol | [Molecular Weight]
373.78 |
| Hazard Information | Back Directory | [Uses]
Amino-Tri-(carboxyethoxymethyl)-methane hydrochloride is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-Tri-(carboxyethoxymethyl)-methan hydrochloride is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1][2]. | [References]
[1] Markus Ribbert, et al. Self coupling recombinant antibody fusion proteins. WO2009013359A2.
[2] David Margulies, et al. Fluorescent molecular sensor for targeting changes in protein surfaces, and methods of use thereof. WO2015166491A2. |
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