| Identification | Back Directory | [Name]
GALANIN (2-29) (RAT) | [CAS]
141696-11-9 | [Synonyms]
GALANIN (2-29) (RAT)
M.W. 3107.42 C139H207N42O40
Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-His-Ala-Ile-Asp-Asn-His-Arg-Ser-Phe-Ser-Asp-Lys-His-Gly-Leu-Thr-NH2 | [Molecular Formula]
C144H210N42O39 | [MDL Number]
MFCD06798978 | [MOL File]
141696-11-9.mol | [Molecular Weight]
3153.47 |
| Chemical Properties | Back Directory | [density ]
1.51±0.1 g/cm3(Predicted) | [storage temp. ]
Desiccate at -20°C | [form ]
Powder | [Water Solubility ]
Soluble to 0.60 mg/ml in water | [Sequence]
Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-His-Ala-Ile-Asp-Asn-His-Arg-Ser-Phe-Ser-Asp-Lys-His-Gly-Leu-Thr-NH2 |
| Hazard Information | Back Directory | [Description]
Peptide agonist for galanin receptors, showing selectivity for GAL2 (Ki values are 85, 9 and 16 nM at rat GAL1, GAL2 and GAL3 receptors respectively). | [Uses]
Galanin (2-29) (rat) inhibits rat pancreatic protein and CCK-8-stimulated amylase secretion. Galanin (2-29) (rat) is an GAL2R agonist (Ki: 3.5 nM)[1][2]. | [References]
[1] Rossowski WJ, et al. Galanin: structure-dependent effect on pancreatic amylase secretion and jejunal strip contraction. Eur J Pharmacol. 1993 Aug 24;240(2-3):259-67. DOI:10.1016/0014-2999(93)90907-y
[2] Wang S, et al. Molecular cloning and pharmacological characterization of a new galanin receptor subtype. Mol Pharmacol. 1997 Sep;52(3):337-43. DOI:10.1124/mol.52.3.337 |
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