| Identification | Back Directory | [Name]
Fozivudine | [CAS]
141790-23-0 | [Synonyms]
Fozivudine
fozivudine tidoxil
(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl (2-decoxy-3-dodecylsulfanylpropyl) hydrogen phosphate | [Molecular Formula]
C35H64N5O8PS | [MDL Number]
MFCD00910983 | [MOL File]
141790-23-0.mol | [Molecular Weight]
745.958 |
| Hazard Information | Back Directory | [Uses]
Fozivudine is useful for preparing nanocontainers for transporting nonpolar and lipophilic substances such as antibiotics. | [in vivo]
Fozivudine tidoxil (BM-211290; 45 mg/kg; PO; twice daily; one day before FIV challenge for a total of six weeks) is effective at lowering plasma- and cell-associated viremia at two weeks post-FIV infection[1]. | Animal Model: | Specific pathogen-free cats at 6 months of age[1] | | Dosage: | 45 mg/kg | | Administration: | PO; twice daily; one day before FIV challenge for a total of six weeks | | Result: | Effective at lowering plasma- and cell-associated viremia at two weeks post-feline immunodeficiency virus (FIV) infection with a trend toward lower plasma- and cell- associated viremia at four and six weeks post-infection (PI).
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| [IC 50]
HIV |
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MedChemExpress
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