| Chemical Properties | Back Directory | [Boiling point ]
905.3±65.0 °C(Predicted) | [density ]
1.28±0.1 g/cm3(Predicted) | [pka]
9.32±0.15(Predicted) | [Sequence]
{2-NH2,3-OH,4-Me-Ph}-Thr-{d-Val}-Pro-{Sar}-Val (Lactone bridge: Thr1-Val5) |
| Hazard Information | Back Directory | [Description]
Protactin is a new antibiotic metabolite and a possible precursor of the actinomycins. | [Uses]
Protactin is a pentapeptide lactone produced by Streptomyces cucumeris strain L703-4 (ATCC 53784) with significant antioxidant properties. Protactin can be converted to actinomycin Zp by ferrocyanide oxidation. Actinomycin Zp exhibits potent antibacterial activity in vitro and has significant antitumor effects against P-388 leukemia in a mouse model[1]. | [References]
[1] Protactin, a new antibiotic metabolite and a possible precursor of the actinomycins |
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CHEMICAL LAND21
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82- 2 -783 - 8063 |
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www.chemicalland21.com |
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