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Clathrin-IN-25 is the most potent clathrin terminal domain-amphiphysin inhibitor reported to date. | [Uses]
Clathrin-IN-3 (Compound 25) is a Clathrin inhibitor (IC50: 6.9 μM). Clathrin-IN-3 potenly inhibits clathrin terminal domain-amphiphysin PPI[1]. | [References]
[1] MacGregor KA, et al. Development of 1,8-naphthalimides as clathrin inhibitors. J Med Chem. 2014 Jan 9;57(1):131-43. DOI:10.1021/jm4015263 |
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