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141979-04-6

141979-04-6 Structure

141979-04-6 Structure
IdentificationBack Directory
[Name]

Ro 31-8588
[CAS]

141979-04-6
[Synonyms]

Ro 31-8588
[Molecular Formula]

C33H56N4O5
[MOL File]

141979-04-6.mol
[Molecular Weight]

588.822
Hazard InformationBack Directory
[Description]

Ro 31-8588 is a hydroxyethylene inhibitor of HIV protease.
[Uses]

Ro 31-8588 is a HIV protease inhibitor with the Ki of 0.3 nM. Ro 31-8588 can be used for study of AIDS[1].
[References]

[1] Graves BJ, et al. The three-dimensional x-ray crystal structure of HIV-1 protease complexed with a hydroxyethylene inhibitor. Adv Exp Med Biol. 1991;306:455-60. DOI:10.1007/978-1-4684-6012-4_58
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