| Identification | Back Directory | [Name]
CAMP-DEPENDENT PROTEIN KINASE, CATALYTIC SUBUNIT | [CAS]
142008-29-5 | [Synonyms]
PKA
KAPB
KAPCB
EC 2.7.1.37
PKA-C-ALPHA
PKA (CATALYTIC SUBUNIT)
CAMP-DEPENDENT PROTEIN KINASE
PROTEIN KINASE A, CATALYTIC SUBUNIT
PROTEIN KINASE A, ALPHA CATALYTIC SUBUNIT
3',5'-CYCLIC AMP DEPENDENT PROTEIN KINASE
PROTEIN KINASE A, CATALYTIC SUBUNIT, MOUSE
CAMP-DEPENDENT PROTEIN KINASE, CATALYTIC SUBUNIT
PROTEIN KINASE A, CATALYTIC SUBUNIT, BOVINE HEART
Anti-KAPCB, C-Terminal antibody produced in rabbit
Protein KinaseA Catalytic Subunit from bovine heart
CYCLIC AMP - DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT (PKA C), RECOMBINANT | [MDL Number]
MFCD00286330 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [form ]
lyophilized (white powder to sticky mass to hard pellet) | [Specific Activity]
≥9units/μg protein (cyclic-AMP is not required for this activity) |
| Hazard Information | Back Directory | [Uses]
Protein Kinase A (PKA) Catalytic Subunit from bovine heart has been used-
- to study PKA-mediated inhibition of IRK1 (inwardly rectifying K+) channels
- in in Vitro PKA pPhosphorylation assay
- in Vitro affinity binding assays
- to study effects of PKA on inspiratory drive currents in functionally active motorneurons
| [General Description]
Protein Kinase A enzyme is composed of two subunits- catalytic and regulatory. The catalytic subunit exists as a monomer in the presence of cAMP and has a molecular weight of 40,862 Da. | [Biochem/physiol Actions]
Protein Kinase A (PKA) controls the transduction of?Hedgehog?signaling and participates in proliferation and fate specification. It phosphorylates several neurotransmitter receptors, transcription factors and constituents of various intracellular signaling pathways. |
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Sigma-Aldrich
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021-61415566 800-8193336 |
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https://www.sigmaaldrich.cn |
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