| Identification | Back Directory | [Name]
2-(2-Aminoethoxy)-5-chloro-N-(2-chloro-4-nitrophenyl)benzamide | [CAS]
1420290-88-5 | [Synonyms]
HJC0152 free base
2-(2-Aminoethoxy)-5-chloro-N-(2-chloro-4-nitrophenyl)benzamide
Benzamide, 2-(2-aminoethoxy)-5-chloro-N-(2-chloro-4-nitrophenyl)- | [Molecular Formula]
C15H13Cl2N3O4 | [MDL Number]
MFCD31704937 | [MOL File]
1420290-88-5.mol | [Molecular Weight]
370.19 |
| Chemical Properties | Back Directory | [Boiling point ]
486.2±45.0 °C(Predicted) | [density ]
1.491±0.06 g/cm3(Predicted) | [storage temp. ]
Store at Room Tem. | [pka]
10.93±0.70(Predicted) |
| Hazard Information | Back Directory | [Uses]
HJC0152 (free base) is an orally active and potent inhibitor of STAT3. HJC0152 (free base) inhibits cell cycle progression and induces apoptosis. HJC0152 (free base) significantly suppresses MDA-MB-231 xenograft tumor growth in mice[1]. | [References]
[1] Chen H, et al. Discovery of O-Alkylamino Tethered Niclosamide Derivatives as Potent and Orally Bioavailable Anticancer Agents. ACS Med Chem Lett. 2013 Feb 14;4(2):180-185. DOI:10.1021/ml3003082 |
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| Company Name: |
Henan Alpha Chemical Co., Ltd.
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0371-55055611 18137792234 |
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https://www.chemicalbook.com/ShowSupplierProductsList31206/0.htm |
| Company Name: |
Nextpeptide Inc
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+86-0571-81612335 +8613336028439 |
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http://www.nextpeptide.com/ |
| Company Name: |
Bide Pharmatech Ltd.
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400-1647117 13681763483 |
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https://www.bidepharm.com/ |
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