| Chemical Properties | Back Directory | [Boiling point ]
753.4±60.0 °C(Predicted) | [density ]
1.38±0.1 g/cm3(Predicted) | [solubility ]
≥25.5 mg/mL in DMSO with gentle warming; insoluble in H2O; insoluble in EtOH | [form ]
solid | [pka]
6.88±0.12(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
(+)-Ketoconazole can be used in pharmacological activity and biological study as ketoconazole stereoisomers differentially induce CYP4501A1 in human and mouse hepatoma. Enantiomerically pure isomer of racemic Ketoconazole (K186000). | [Definition]
ChEBI: (2R,4S)-ketoconazole is a cis-1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine which dioxolane moiety has (2R,4S)-configuration. It is an enantiomer of a (2S,4R)-ketoconazole. | [Biological Activity]
(+)-ketoconazole is an imidazole anti-fungal agent, a cyp3a4 inhibitor. |
|
| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
BOC Sciences
|
| Tel: |
16314854226 |
| Website: |
www.bocsci.com |
| Company Name: |
Musechem
|
| Tel: |
+1-800-259-7612 |
| Website: |
www.musechem.com |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|