| Identification | Back Directory | [Name]
5-Chloro-2-(9H-fluoren-9-yl)-4-(4-methoxyphenoxy)-3(2H)-pyridazinone | [CAS]
1421365-63-0 | [Synonyms]
ML250
CYM50769
CYM50769 (ML250)
CYM50769 >=98% (HPLC)
5-Chloro-2-(9H-fluoren-9-yl)-4-(4-methoxyphenoxy)-3(2H)-pyridazinone
3(2H)-Pyridazinone, 5-chloro-2-(9H-fluoren-9-yl)-4-(4-methoxyphenoxy)-
CYM 50769,ATDC5,CYM-50769,Inhibitor,NPBWR1,CYM50769,GPR7,Endochondral bone formation,inhibit | [Molecular Formula]
C24H17ClN2O3 | [MDL Number]
MFCD27991286 | [MOL File]
1421365-63-0.mol | [Molecular Weight]
416.86 |
| Chemical Properties | Back Directory | [Boiling point ]
552.3±60.0 °C(Predicted) | [density ]
1.34±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: soluble20mg/mL, clear | [form ]
powder | [pka]
-2.72±0.20(Predicted) | [color ]
white to beige |
| Hazard Information | Back Directory | [Uses]
CYM 50769 is a non-peptidic selective antagonist of neuropeptides B and W receptor 1 (NPBWR1). CYM 50769 can attenuates the NPW-23-induced cell proliferation in ATDC5. CYM 50769 can be used for researching endochondral bone formation[1]. | [storage]
Store at -20°C | [References]
[1] Guerrero M, et al. SAR analysis of novel non-peptidic NPBWR1 (GPR7) antagonists. Bioorg Med Chem Lett. 2013 Feb 1;23(3):614-9. DOI:10.1016/j.bmcl.2012.12.030 |
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