| Identification | Back Directory | [Name]
13-Acetyl-9-dihydrobaccatin III | [CAS]
142203-65-4 | [Synonyms]
19-DHB
9-DHAB III
Cabazitaxel Impurity 55
9-Dideacetyl baccatin VI
7,9-Dideacetylbaccatin VI
Cephalomannine Impurity 1
13-Acetyl-9-dihydro bacatin-Ⅲ
13-Acetyl-9-dihydrobaccatin III
13-Acetyl-9(R)-dihydrobaccatin-III
9-DIHYDRO-13-ACETYL BACCATIN(9-DHB)
9-Dihydro-13-acetyl baccatinⅢ(9-DHB)
13-Acetyl-9-Dihydrobaccatin Iii (9-Dhb)
9-DIHYDRO-13-ACETYL BACCATIN III(9-DHB)
13-Acetyl-9-dihydrobaccatin III USP/EP/BP
9-Dihydro-13-acetylbaccatinIII from Taxus canadensis
2a,3,4,4a,5,6,9,10,12,12a-Decahydro-4a,8,13,13-tetramethyl-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxete-4,5,6,9,11,12,12b-heptol (2aR,4S,4aS,5R,6R,9S,11S,12S,12aR,12bS)-6,9,12b-triacetate 12-benzoate
7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete-4,5,6,9,11,12,12b-heptol, 2a,3,4,4a,5,6,9,10,12,12a-decahydro-4a,8,13,13-tetramethyl-, 6,9,12b-triacetate 12-benzoate, (2aR,4S,4aS,5R,6R,9S,11S,12S,12aR,12bS)- | [Molecular Formula]
C33H42O12 | [MDL Number]
MFCD01310496 | [MOL File]
142203-65-4.mol | [Molecular Weight]
630.68 |
| Chemical Properties | Back Directory | [Melting point ]
171-175°C | [Boiling point ]
704.5±60.0 °C(Predicted) | [density ]
1.36±0.1 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,2-8°C | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
12.61±0.70(Predicted) | [color ]
White | [InChIKey]
WPPPFZJNKLMYBW-FAEUQDRCSA-N | [SMILES]
O1C[C@@]2(OC(=O)C)[C@@]3([H])[C@H](OC(=O)C4=CC=CC=C4)[C@@]4(O)C(C)(C)C(=C(C)[C@@H](OC(=O)C)C4)[C@@H](OC(=O)C)[C@H](O)[C@]3(C)[C@@H](O)C[C@@]12[H] |
| Hazard Information | Back Directory | [Description]
13-acetyl-9-Dihydrobaccatin III is a taxane originally isolated from T. canadensis.1 It inhibits proliferation of P388 leukemia cells with an IC50 value of 20 μg/ml. | [Chemical Properties]
White crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Taxus chinensis. | [Uses]
13-Acetyl-9-dihydrobaccatin-III is an apoptosis inducer. | [References]
[1] GEEWANANDA P. GUNAWARDANA. Isolation of 9-Dihydro-13-acetylbaccatin III from Taxus canadensis[J]. Journal of Natural Products , 1992, 55 11: 1686-1689. DOI: 10.1021/np50089a022 |
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