| Identification | Back Directory | [Name]
Antimalarial compound 49c | [CAS]
1422207-75-7 | [Synonyms]
Antimalarial agent 20
Antimalarial compound 49c
Benzamide, N-[(1S,2R)-2-hydroxy-3-[[(1R)-1-phenylethyl]amino]-1-(phenylmethyl)propyl]-4-[(4-methyl-1-piperazinyl)carbonyl]- | [Molecular Formula]
C31H38N4O3 | [MOL File]
1422207-75-7.mol | [Molecular Weight]
514.66 |
| Hazard Information | Back Directory | [Uses]
Antimalarial agent 20 (Compound 49c) is an antimalarial agent with an IC50 of 0.6 nM against P. falciparum NF54 parasite strain in the NF54 albumax assay[1]. | [References]
[1] Ciana CL, et al. Novel in vivo active anti-malarials based on a hydroxy-ethyl-amine scaffold. Bioorg Med Chem Lett. 2013 Feb 1;23(3):658-62. DOI:10.1016/j.bmcl.2012.11.118 |
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