| Identification | Back Directory | [Name]
FUMONISIN B3 | [CAS]
1422359-85-0 | [Synonyms]
FUMONISIN B3
Fumonisin B3 from Fusarium moniliforme
Fumonisin B3 solution in Methanol, 10μg/mL
1,2,3-Propanetricarboxylic acid, 1,1'-[(1S,2R)-1-[(2S,4R,11S,12S)-12-amino-4,11-dihydroxy-2-methyltridecyl]-2-[(1R)-1-methylpentyl]-1,2-ethanediyl] ester, (2R,2'R)- | [Molecular Formula]
C34H59NO14 | [MDL Number]
MFCD08458745 | [MOL File]
1422359-85-0.mol | [Molecular Weight]
705.83 |
| Chemical Properties | Back Directory | [Boiling point ]
867.0±65.0 °C(Predicted) | [density ]
1.222±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO (Very Slightly), Methanol (Slightly) | [form ]
A powder | [pka]
3?+-.0.23(Predicted) |
| Hazard Information | Back Directory | [Description]
Fumonisin B3 (FB3) is a mycotoxin that has been found in Fusarium. It is cytotoxic to primary rat hepatocytes when used at concentrations of 125, 250, and 500 μM. Dietary administration of FB3 (0.05%) for 14 or 21 days induces hepatocyte nodules, a marker of cancer initiation, in rats. FB3 has been detected in corn and corn-based foods and livestock feeds. | [Uses]
Fumonisin B3 is a mycotoxin present in corn. Fungal metabolite believed to cause leukoencephalomalacia in horses. | [storage]
Store at -20°C | [References]
[1] J. RHEEDER H V W Marasas. Production of Fumonisin Analogs by Fusarium Species[J]. Applied and Environmental Microbiology, 2002, 68 1: 2101-2105. DOI: 10.1128/aem.68.5.2101-2105.2002
[2] W.C.A. GELDERBLOM . Structure-activity relationships of fumonisins in short-term carcinogenesis and cytotoxicity assays[J]. Food and Chemical Toxicology, 1993, 31 6: Pages 407-414. DOI: 10.1016/0278-6915(93)90155-r
[3] BULLERMAN L B. Occurrence of Fusarium and fumonisins on food grains and in foods.[J]. Advances in experimental medicine and biology, 1996, 392: 27-38. DOI: 10.1007/978-1-4899-1379-1_3 |
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