| Identification | Back Directory | [Name]
Flufenacet | [CAS]
142459-58-3 | [Synonyms]
CS-141
FLUAMID
FOE 5043
Hsdb 7011
Fluthiamid
FLUFENACET
FLUTHIAMIDE
Thiafluamide
Bay-foe 5043
flufenacet 98%
Flufenacet [iso]
hiadiazol-2-yl)oxy)-
Heteroacryloxyacetamide
FLUFENACET PESTANAL, 100MG
FlufenacetSolution,100mg/L,5x1ml
Einecs annex I index 613-164-00-9
Flufenacet@100 μg/mL in Acetonitrile
Flufenacet@1000 μg/mL in Acetonitrile
acetamide,n-(4-fluorophenyl)-n-(1-methylethyl)-2-((5-(trifluoromethyl)-1,3,4-t
4`-fluoro-N-isopropyl-2-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yloxy]acetanilide
N-(4-FLUOROPHENYL)-N-ISOPROPYL-2-[5-(TRIFLUOROMETHYL)-1,3,4-THIADIAZOL-2-YLOXY]ACETAMIDE
n-(4-fluorophenyl)-n-(1-methylethyl)-2-((5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)oxy)-acetamid
N-(4-Fluorophenyl)-N-(1-methylethyl)-2-[[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]oxy]acetamide
Acetamide, N-(4-fluorophenyl)-N-(1-methylethyl)-2-((5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)oxy)-
flufenacet (ISO) N-(4-fluorophenyl)-N-isopropyl-2-(5-trifluoromethyl-[1,3,4]thiadiazol-2-yloxy)acetamide
Flufenacet AcetaMide,N-(4-fluorophenyl)-N-(1-Methylethyl)-2-((5-(trifluoroMethyl)-1,3,4-thiadiazol-2-yl)oxy)- | [EINECS(EC#)]
604-290-5 | [Molecular Formula]
C14H13F4N3O2S | [MDL Number]
MFCD01751191 | [MOL File]
142459-58-3.mol | [Molecular Weight]
363.33 |
| Chemical Properties | Back Directory | [Melting point ]
75-77° | [Boiling point ]
401.5±55.0 °C(Predicted) | [density ]
1.312 g/cm3 | [storage temp. ]
0-6°C | [solubility ]
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) | [form ]
neat | [pka]
0.31±0.50(Predicted) | [BRN ]
8787751 | [Henry's Law Constant]
1.7×103 mol/(m3Pa) at 25℃, HSDB (2015) | [Major Application]
agriculture
environmental | [InChI]
InChI=1S/C14H13F4N3O2S/c1-8(2)21(10-5-3-9(15)4-6-10)11(22)7-23-13-20-19-12(24-13)14(16,17)18/h3-6,8H,7H2,1-2H3 | [InChIKey]
IANUJLZYFUDJIH-UHFFFAOYSA-N | [SMILES]
C(N(C1=CC=C(F)C=C1)C(C)C)(=O)COC1=NN=C(C(F)(F)F)S1 | [EPA Substance Registry System]
Flufenacet (142459-58-3) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,N | [Risk Statements ]
22-43-48/22-50/53 | [Safety Statements ]
13-24-37-60-61 | [RIDADR ]
UN 3077 | [WGK Germany ]
1 | [RTECS ]
AC2845000 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral
Aquatic Acute 1
Aquatic Chronic 1
Skin Sens. 1
STOT RE 2 | [Hazardous Substances Data]
142459-58-3(Hazardous Substances Data) | [Toxicity]
LD50 in rats (mg/kg): 589-1617 orally; >2000 dermally; LD50 orally in mice, bobwhite quail, mallard duck: 1331-1756, 1608, >2000 mg/kg; LC50 in sunfish, rainbow trout, sheepshead minnow: 2.1-2.4, 3.5-5.8, 3.3 mg/l (Hall) |
| Hazard Information | Back Directory | [Description]
Flufenacet is a selective herbicide. It is moderately soluble in water, is not highly volatile but may, under certain conditions, be persistent in soil and water/sediment systems. It is moderately toxic to humans via the oral route and is considered to be a skin sensitiser. With the exception of honeybees where the toxicity is low, flufenacet is either moderately or highly toxic to most fauna and flora. | [Uses]
Flufenacet is an anilide based herbicide that is applied to the soil surface or incorporated before the crop is emerged. Flufenacet is often used in field corn, corn grown for silage or soybeans to co
ntrol annual grasses and broadleaf weeds. | [Uses]
Pre-emergent herbicide. | [Definition]
ChEBI: An aromatic amide that is acetamide in which the amino hydrogens have been replaced by a propan-2-yl and 4-fluorophenyl groups while the methyl hydrogen is replaced by a [5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]oxy group. | [Production Methods]
Flufenacet is commercially produced through a multi-step chemical synthesis involving halogenated aromatic compounds and acetamide derivatives. The process typically includes the formation of a substituted aniline intermediate, which is then reacted with chloroacetyl chloride or similar reagents to introduce the acetamide functionality. Fluorination steps are also involved to incorporate trifluoromethyl groups, which contribute to the herbicide’s potency and environmental persistence. | [Agricultural Uses]
Herbicide: Flufenacet is applied to the soil surface or incorporated
pre-emergence in field corn, corn grown for silage,
or soybeans to control certain annual grasses and broadleaf
weeds. Not listed for use in EU countries. Registered
for use in the U.S. | [Trade name]
AXIOM® Thiafluamide; DOMAIN®;
EPIC®; FOE 5043® technical | [Mechanism of action]
Selective with meristematic activity. Inhibition of very long chain fatty acids (VLCFA, inhibition of cell division) | [Pesticide Type]
Herbicide |
|
|