| Identification | Back Directory | [Name]
Glyasperin C | [CAS]
142474-53-1 | [Synonyms]
Glyasperin C
Glyasperin C - Glycyrrhiza uralensis (liquorice)
1,3-Benzenediol, 4-[(3R)-3,4-dihydro-7-hydroxy-5-methoxy-6-(3-methyl-2-buten-1-yl)-2H-1-benzopyran-3-yl]- | [Molecular Formula]
C21H24O5 | [MOL File]
142474-53-1.mol | [Molecular Weight]
356.41 |
| Chemical Properties | Back Directory | [Boiling point ]
559.3±50.0 °C(Predicted) | [density ]
1.243±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
9?+-.0.40(Predicted) | [color ]
Off-white to light yellow | [InChI]
InChI=1S/C21H24O5/c1-12(2)4-6-16-19(24)10-20-17(21(16)25-3)8-13(11-26-20)15-7-5-14(22)9-18(15)23/h4-5,7,9-10,13,22-24H,6,8,11H2,1-3H3/t13-/m0/s1 | [InChIKey]
RCZMWVKBVFOCEE-ZDUSSCGKSA-N | [SMILES]
C1(O)=CC=C([C@H]2CC3=C(OC)C(C/C=C(/C)\C)=C(O)C=C3OC2)C(O)=C1 |
| Hazard Information | Back Directory | [Uses]
Glyasperin C is a potent and reversible noncompetitive inhibitor of neuraminidase with an IC50 of 20% at 200 μM. Glyasperin C is a polyphenol isolated from the roots of Glycyrrhiza uralensis[1]. | [Definition]
ChEBI: A methoxyisoflavan that is (R)-isoflavan substituted by a methoxy group at position 5, hydroxy groups at positions 7, 2' and 4' and a prenyl group at position 6. It has been isolated from Glycyrrhiza uralensis. | [References]
[1] Ryu YB, et al. Inhibition of neuraminidase activity by polyphenol compounds isolated from the roots of Glycyrrhiza uralensis. Bioorg Med Chem Lett. 2010;20(3):971-974. DOI:10.1016/j.bmcl.2009.12.106 |
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