| Identification | Back Directory | [Name]
IPI3063 | [CAS]
1425043-73-7 | [Synonyms]
IPI3063
IPI 3063;IPI3063
(S)-4-amino-6-((1-(2-isopropyl-8-(1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-1-oxo-1,2-dihydroisoquinolin-3-yl)ethyl)amino)pyrimidine-5-carbonitrile
4-Amino-6-[[(1S)-1-[8-(1,6-dihydro-1-methyl-6-oxo-3-pyridinyl)-1,2-dihydro-2-(1-methylethyl)-1-oxo-3-isoquinolinyl]ethyl]amino]-5-pyrimidinecarbonitrile
5-Pyrimidinecarbonitrile, 4-amino-6-[[(1S)-1-[8-(1,6-dihydro-1-methyl-6-oxo-3-pyridinyl)-1,2-dihydro-2-(1-methylethyl)-1-oxo-3-isoquinolinyl]ethyl]amino]- | [Molecular Formula]
C25H25N7O2 | [MDL Number]
MFCD29918875 | [MOL File]
1425043-73-7.mol | [Molecular Weight]
455.51 |
| Hazard Information | Back Directory | [Uses]
4-Amino-6-[[(1S)-1-[8-(1,6-dihydro-1-methyl-6-oxo-3-pyridinyl)-1,2-dihydro-2-(1-methylethyl)-1-oxo-3-isoquinolinyl]ethyl]amino]-5-pyrimidinecarbonitrile, is a potent and selective PI3K p110δ inhibitor. | [IC 50]
p110δ: 2.5 nM (IC50); p110α: 1170 nM (IC50); p110β: 1508 nM (IC50); p110γ: 2187 nM (IC50) |
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