| Identification | Back Directory | [Name]
squalestatin 3 | [CAS]
142505-92-8 | [Synonyms]
squalestatin 3
Squalestatin C
L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 11-acetate, (7S)- | [Molecular Formula]
C25H30O13 | [MOL File]
142505-92-8.mol | [Molecular Weight]
538.498 |
| Hazard Information | Back Directory | [Uses]
Squalestatin 3 is a secondary metabolite, which can be isolated from Phoma. Squalestatin 3 is an inhibitor for squalene synthase with an IC50 of 6 nM[1]. | [References]
[1] Watson N S, et al. The squalestatins: potent inhibitors of squalene synthase. The role of the tricarboxylic acid moiety[J]. Bioorganic & Medicinal Chemistry Letters, 1993, 3(12): 2541-2546. |
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