| Identification | Back Directory | [Name]
2-Quinoxalineacetamide, α-cyano-3-(hexahydro-1H-azepin-1-yl)-N-[1-(4-methoxyphenyl)-2-(4-morpholinyl)ethyl]- | [CAS]
1425051-22-4 | [Synonyms]
hIgG–hFc receptor-IN-1
2-Quinoxalineacetamide, α-cyano-3-(hexahydro-1H-azepin-1-yl)-N-[1-(4-methoxyphenyl)-2-(4-morpholinyl)ethyl]- | [Molecular Formula]
C30H36N6O3 | [MOL File]
1425051-22-4.mol | [Molecular Weight]
528.66 |
| Hazard Information | Back Directory | [Uses]
hIgG–hFc receptor-IN-1 (comp 66) is a human immunoglobulin G–human neonatal Fc receptor (hIgG–hFcRn) protein-protein interaction inhibitor, with an IC50 of 2 μM [1]. | [References]
[1] Zhaolin Wang, et al. Discovery and structure-activity relationships of small molecules that block the human immunoglobulin G-human neonatal Fc receptor (hIgG-hFcRn) protein-protein interaction. Bioorg Med Chem Lett. 2013 Mar 1;23(5):1253-6. DOI:10.1016/j.bmcl.2013.01.014 |
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