| Identification | Back Directory | [Name]
L-690,330 | [CAS]
142523-38-4 | [Synonyms]
L-690,330
[1-(4-HYDROXYPHENOXY)ETHYLIDENE]BISPHOSPHONIC ACID
Phosphonic acid, P,P'-[1-(4-hydroxyphenoxy)ethylidene]bis- | [Molecular Formula]
C8H12O8P2 | [MDL Number]
MFCD00673897 | [MOL File]
142523-38-4.mol | [Molecular Weight]
298.12 |
| Chemical Properties | Back Directory | [Boiling point ]
696.9±65.0 °C(Predicted) | [density ]
1.787±0.06 g/cm3(Predicted) | [storage temp. ]
Store at RT | [solubility ]
Water:19.65(Max Conc. mg/mL);65.9(Max Conc. mM) | [form ]
Solid | [pka]
1.44±0.10(Predicted) | [color ]
White to off-white | [Water Solubility ]
Soluble to 20 mM in water |
| Hazard Information | Back Directory | [Uses]
L-690,330 is an inositol monophosphatase inhibitor in vitro and in vivo. | [Definition]
ChEBI: [1-(4-hydroxyphenoxy)-1-phosphonoethyl]phosphonic acid is a 1,1-bis(phosphonic acid). | [Biological Activity]
A potent inhibitor of inositol monophophatase, stable to hydrolysis. | [in vivo]
L-690330 (intracerebroventricular?injection; 0.1 μmol) has no effects on their motor activity and coordination in the beam walking, except a reduction in time spent in light in the dark/light test[3]. | Animal Model: | Eight-week-old male ICR mice[3] | | Dosage: | 0.1 μmol | | Administration: | Intracerebroventricular?injection | | Result: | Did not effect mice well-being by i.c.v injection. |
| [storage]
Store at RT |
|
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|