| Identification | Back Directory | [Name]
Sageone | [CAS]
142546-15-4 | [Synonyms]
Sageone
2,3,9,10-Tetrahydro-5,6-dihydroxy-1,1-dimethyl-7-(1-methylethyl)-4(1H)-phenanthrenone
4(1H)-Phenanthrenone, 2,3,9,10-tetrahydro-5,6-dihydroxy-1,1-dimethyl-7-(1-methylethyl)- | [Molecular Formula]
C19H24O3 | [MDL Number]
MFCD32644993 | [MOL File]
142546-15-4.mol | [Molecular Weight]
300.39 |
| Chemical Properties | Back Directory | [Boiling point ]
485.9±45.0 °C(Predicted) | [density ]
1.20±0.1 g/cm3(Predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
powder | [pka]
9.26±0.40(Predicted) | [color ]
Red |
| Hazard Information | Back Directory | [Description]
Sageone shows antiviral activity. | [Uses]
Sageone, a diterpene that can be isolated from Rosmarinus officinalis, is a antiviral and anticancer agent. Sageone induces apoptosis in SNU-1 human gastric cancer cells[1][2]. | [Definition]
ChEBI: Sageone is a diterpenoid. | [target]
Antifection | [References]
[1] MASAHIRO TADA, et al. ANTIVIRAL DITERPENES FROM SAL VIA OFFZCZNALZS. Phytochemistry. Volume 35, Issue 2, January 1994, Pages 539-541.
[2] Sabina Shrestha, et al. Sageone, a diterpene from Rosmarinus officinalis, synergizes with cisplatin cytotoxicity in SNU-1 human gastric cancer cells. Phytomedicine. 2016 Dec 1;23(13):1671-1679. DOI:10.1016/j.phymed.2016.09.008 |
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