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1426336-36-8

1426336-36-8 Structure

1426336-36-8 Structure
IdentificationBack Directory
[Name]

Nav1.7 blocker 1
[CAS]

1426336-36-8
[Synonyms]

Nav1.7 blocker 1
[Molecular Formula]

C22H21FN4O4
[MOL File]

1426336-36-8.mol
[Molecular Weight]

424.43
Chemical PropertiesBack Directory
[Boiling point ]

563.4±50.0 °C(predicted)
[density ]

1.340±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka]

14.31±0.50(predicted)
Hazard InformationBack Directory
[Uses]

Nav1.7 blocker 1 (example 41) is a Na+ channel (Nav) blocker with an IC50 value of 0.037 μM. Nav1.7 blocker 1 can be used for the study of pain, including neuropathic pain, postoperative pain, inflammatory pain, and so on[1].
[References]

[1] Chiyou Ni, et al. Pyrimidines as sodium channel blockers. WIPO. Patent. WO2013030665. 2013-03-07
1426336-36-8 suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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