| Hazard Information | Back Directory | [Description]
L 703014 is a fibrinogen receptor antagonist. | [Uses]
L-703014 is a fibrinogen receptor antagonist, with the IC50 of 94 nM, that acts as a novel parenteral and potential oral antithrombotic agent[1][2]. | [References]
[1] J S Barrett, et al. Pharmacokinetics and Pharmacodynamics of L-703,014, a Potent Fibrinogen Receptor Antagonist, After Intravenous and Oral Administration in the Dog. Pharm Res. 1994 Mar;11(3):426-31. DOI:10.1023/a:1018973323039
[2] R M Scarborough, et al. Platelet glycoprotein IIb-IIIa antagonists as prototypical integrin blockers: novel parenteral and potential oral antithrombotic agents. J Med Chem. 2000 Sep 21;43(19):3453-73. DOI:10.1021/jm000022w |
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